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Some diseases leave the red blood cells fragile or stiff and inflexible. Cells which break easily and cells that are too stiff to bend and squeeze through the capillaries and the tiny filter-like pores in the spleen are destroyed. If there are too many such cells, the bone marrow can't keep up and too few red cells stay in the circulation.
Beta Thalassemia |
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Alpha Thalassemia |
When a thalassemia prevents hemoglobin from forming properly the blood cells may become misshaped and fragile.
(Index)
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