Platelet Immunology Laboratory
Heparin Antibody Tests
Heparin/PF4 IgG ELISA
An enzyme linked immunosorbant assay (ELISA) using a complex of heparin and Platelet Factor 4 (PF4) is used to capture antibody developed during type II Heparin-Induced Thrombocytopenia (HIT).
Heparin/PF4 IgG ELISA (confirmation)
Reflex testing for confirmation of positive heparin antibody with the addition of high dose heparin as an inhibitory step in the heparin/PF4 IgG ELISA.
Heparin/PF4 ELISA (IgG, IgA, and IgM)
In some cases, HIT may be due to an IgA or IgM heparin associated antibody. If clinically indicated, test can be requested with anti-IgG, -A and –M.