- Transaction Code: 3103-00/3104-00 (for Mother)
- CPT Code (Suggested): 86850, 86900/86901
- Transaction Code: 3103-00/3125-00 (for Baby)
- CPT Code (Suggested): 86880, 86900/86901
This profile is recommended to evaluate suspected or known hemolytic disease of the newborn (HDN). Severe HDN (i.e., requiring exchange transfusion) is most commonly caused by alloimmunization to Rh (usually D or c) or Kell red cell antigens. Duffy (Fya) and Kidd (Jka, Jkb) are rarely involved in severe HDN. Clinically mild HDN is most often associated with ABO incompatibility between mother and fetus. Testing includes ABO, Rh, Indirect Antiglobulin Test (antibody screen) on maternal sample and fetal bleed screen, if indicated. Includes ABO, Rh, and Direct Antiglobulin Test on infant sample.
- Sample Required: For mother: 7 ml EDTA. For baby: prefer EDTA, 7 ml cord blood or 1-2 microtainers peripheral blood (prefer EDTA)
- Normal Test Values: See individual tests
- Analytic Time: 24 hours if weekday; 48 hours if weekend
- Days Test is Set Up: Monday through Sunday
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