- Transaction Code: 3102-00
- CPT Code: 86901
Semiquantitative method for determining serum concentration of clinically significant IgG (non-ABO) antibodies. Serial, two-fold dilutions of serum are tested against red cells carrying the antigen of interest (e.g., D, K) using the indirect antiglobulin method. Result is expressed as the reciprocal of the highest serum dilution which still shows (1+) agglutination. This test is used to monitor serum alloantibody levels in previously sensitized pregnant women for prenatal management of hemolytic disease of the newborn (HDN). In women with Rh alloimmunization, anti-D levels greater or equal to 16 are generally considered an indication for invasive fetal testing.
- Sample Required: 7 ml EDTA
- Normal Test Values: Interpretation depends on clinical setting
- Analytic Time: 24 hours if weekday; 48 hours if weekend
- Days Test is Set Up: Monday through Sunday
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