- Transaction Code: 3125-00
- CPT Code (Suggested): 86880
Detects the presence of red blood cell-bound IgG and/or complement by agglutination using an antiglobulin (Coombs) reagent. Positive results can occur in patients with autoimmune hemolytic anemia, drug-induced immune hemolysis (e.g., alpha-methyldopa, procainamide), hemolytic transfusion reactions, or hemolytic disease of the newborn. (See DAT Table) Positive results can also occur due to non-specific IgG absorption (e.g., hypergamma-globulinemia), and occasionally in otherwise healthy individuals. Extended evaluation may include elution and absorption studies.
- Sample Required: 7 ml EDTA
- Normal Test Values: Negative
- Analytic Time: 24 hours if weekday; 48 hours if weekend
- Days Test is Set Up: Monday through Sunday
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