William E. Hobbs' Laboratory

"The ability to look at a clinical problem faced by patients, study it in the lab, and bring a new solution back to the clinic to benefit patients is incredibly rewarding."
William E. Hobbs, MD, PhD

Research in the Hobbs laboratory is primarily focused on the interaction of red blood cells with von Willebrand Factor (VWF) and their effect on blood clotting in individuals with sickle cell disease and in those who abuse cocaine. Additional research focuses on mechanisms by which endothelial cells (the thin layer of cells that line blood vessels) secrete VWF.

Areas of Study

The mechanisms of increased VWF reactivity in sickle cell disease
Development of optimized transfusion practices that support sickle cell disease patients, who are at increased risk for transfusion
The mechanisms underlying increased risk of thrombosis (blood clots), strokes, and heart attacks in individuals who abuse cocaine
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Dr. Hobbs' Background

Joined the Puget Sound Blood Center in 2010 after completing fellowship training in Hematology/Oncology at the University of Washington.
Director of the Adult Sickle Cell Disease Clinic at the University of Washington School of Medicine

William E. Hobbs, MD, PhD,
Assistant Member
Puget Sound Blood Center
Research Institute

Acting Assistant Professor
University of Washington
Department. of Medicine
Hematology Division

Puget Sound Blood Center
Research Institute
1551 Eastlake Avenue E.
Seattle, WA 98102

Email: williamh@psbc.org
Phone: (206) 568-2208
FAX: (206) 587-6056

Rachel A. Sessum
Administrative Specialist
Email: rachels@psbc.org
Phone: (206) 568-2246
Fax: (206) 587-6056