Note: K.P. Pratt published under the name K.A. Palmer prior to 1995

Refereed Journals (View Book Chapters)

1. Ettinger RA, James EA, Kwok WW, Thompson AR, Pratt KP. "HLA-restricted T-cell responses to FVIII epitopes in a mild haemophilia A family with missense mutation FVIII-A2201P." Haemophilia. In press.

2. Ettinger RA, James EA, Kwok WW, Thompson AR, Pratt KP (2009). "Lineages of human T-cell clones, including TH17/TH1 cells, isolated at different stages of anti-factor VIII immune responses." Blood 114: 1423-8.

3. Pratt KP, Thompson AR (2009). "B-Cell and T-Cell Epitopes in Anti-factor VIII Immune Responses." Clin Rev Allergy Immunol 37: 80-95.

4. Sirocova N, Tsourea V, Vicol M, Barbacaru N, Nakaya SM, Thompson AR, Pratt KP (2009). "Factor VIII mutations in 42 Moldovan haemophilia A families, including 12 that are novel". Haemophilia 15:942-51.

5. Planque S, Escobar MA, Smith KC, Taguchi H, Nishiyama Y, Donnachie E, Pratt KP, Paul S (2008) "Covalent inactivation of factor VIII antibodies from hemophilia A patients by an electrophilic FVIII Analog". J Biol Chem. 283:11876-86.

6. Hsu T-C, Pratt KP, Thompson AR (2008) "The factor VIII C1 domain contributes to platelet binding." Blood 111:2399-407.

7. *James EA, Kwok WW, Thompson AR, Pratt KP (2007) "Analysis of CD4 T-cell responses to FVIII in a mild hemophilia A patient indicates early loss of tolerance to a C2 domain self peptide and sustained loss of tolerance to the wild-type peptide", J. Thromb Hemost. 5:2399-47.

8. Sahud M, Pratt KP, Zhukov O, Qu K, Thompson AR (2007) "ELISA system for detection of immune responses to factor VIII: A study of 246 samples and correlation with the Bethesda assay." Hemophilia 13, 317-22.

9. Rawle FE, Pratt KP, Lanelle A, Weiner H, Lillicrap D (2006) "Induction of immune tolerance to factor VIII through prior mucosal exposure to the factor VIII C2 domain." J Thromb Hemostas 4: 2172-9.

10. Pratt KP, Qian J, Ellaban E, Okita, DK, Diethelm-Okita BM, Conti-Fine, BM Scott, DW (2004) "Immunodominant T-cell epitopes in the Factor VIII C2 domain are located within an inhibitory antibody binding site." Thrombos Haemost 92, 522-8.

11. Fuentes-Prior P, Fujikawa K, Pratt KP (2002) "New insights into binding interfaces of coagulation factors V and VIII and their homologues - lessons from high-resolution crystal structures", Current Protein and Peptide Science, 3, 313-9.

12. *Spiegel PC, Jr., Jacquemin M, Saint-Remy J-MR, Stoddard BL, Pratt, KP (2001) Plenary paper: "Structure of a factor VIII C2-domain - Immunoglobulin G4? Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII", Blood 98, 13-19.

13. Pratt KP (2000) "Relating structure to function: the role of the C2 domain in Factor VIII", Current Opinion in Drug Discovery and Development 3, 1367-77.

14. Liu, M-L, Shen BW, Nakaya S, Pratt KP, Takeshima K, Davie EW, Fujukawa K, Stoddard BL, Thompson AR (2000) "Hemophilic factor VIII C1- and C2- domain missense mutations and their modeling to the 1.5-angstrom human C2-domain crystal structure", Blood 96, 979-87.

15. *Pratt KP, Shen BW, Takeshima K, Davie EW, Fujikawa K, Stoddard BL (1999) "Structure of the C2 domain of human factor VIII at 1.5 angstrom resolution", Nature 402, 439-42.

16. Côté HCF, Lord ST, Pratt KP (1998) "Gamma-Chain Dysfibrinogenemias: Molecular Structure-Function Relationships of Naturally-Occurring Mutations in the Gamma Chain of Human Fibrinogen", Blood 92, 2195-212.

17. Côté HCF, Pratt KP, Davie EW Chung DW (1997) "The primary polymerization site in fibrinogen is separate from the calcium-binding site", J. Biol. Chem. 272, 23792-8.

18. Yee VC, Pratt KP, Côté HCF, LeTrong I, Chung DW, Davie EW, Stenkamp RE, Teller DC (1997) "Crystal Structure of a 30 kDa carboxyl terminal fragment from the gamma chain of human fibrinogen", Structure 5, 125-38.

19. *Pratt KP, Côté HCF, Chung DW, Stenkamp RE, Davie EW (1997) "The primary fibrin polymerization pocket: Three-dimensional structure of a 30-kDa C-terminal Gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro. Proc. Natl. Acad. Sci. USA 94, 7176-84. .

20. Allen SC, Acharya KR, Palmer KA, Shapiro R, Vallee B, Scheraga HA (1994) "A comparison of the predicted and X-ray structures of angiogenin. Implications for further studies of model building of homologous proteins", J. Protein Chem. 13, 649-58.

21. Zagari A, Palmer KA, Gibson KD, Némethy G, Scheraga HA (1994) "The effect of the L-azetidine-2-carboxylic acid residue on protein conformation. IV. Local substitutions in the collagen triple helix", Biopolymers 34, 51-60.

22. Némethy G, Gibson KD, Palmer KA, Yoon CN, Paterlini G, Zagari A, Rumsey S, Scheraga HA (1992) "Energy Parameters on Polypeptides. 10. Improved Geometrical Parameters and Nonbonded Interactions for use in the ECEPP/3 Algorithm, with Application to Proline-containing Peptides", J. Phys. Chem. 96, 6472-84.

23. Perrot G, Cheng B, Gibson KD, Vila J, Palmer KA, Nayeem B, Maigret B, Scheraga, HA (1992) "MSEED: A Program for the Rapid Analytical Determination of Accessible Surface Areas and their Derivatives", J. Computational Chem. 13, 329-50.

24. Palmer KA, Scheraga HA (1991) "Standard-Geometry Chains Fitted to X-ray Derived Structures: Validation of the Rigid-Geometry Approximation. I. Chain Closure through a Limited Search of "Loop" Conformations", J. Computational Chem. 12, 505-26.

25. *Palmer KA, Scheraga HA (1991) "Standard-Geometry Chains Fitted to X-ray Derived Structures: Validation of the Rigid-Geometry Approximation. II. Systematic Searches for Protein Loops: Applications to Bovine Pancreatic Ribonuclease A and Human Lysozyme" (1992) J. Computational Chem. 13, 329-50.

26. Palmer KA, Scheraga HA, Riordan JF, Vallee BL (1986) "A Preliminary Structure of the Protein Angiogenin" Proc. Natl. Acad. Sci. USA 83, 1965-9.

Book Chapters

1. Chung DW. Pratt KP, Ichinose A (2001) "Disorders of Fibrinogen and Factor XIII", in: The Metabolic and Molecular Bases of Inherited Disease, 8th Edition, McGraw-Hill, Inc., 4345-4366.