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Research: Pratt Lab Publications

Note: K.P. Pratt published under the name K.A. Palmer prior to 1995

Pratt K.P., Qian J., Ellaban E., Okita, D.K., Diethelm-Okita B.M., Conti-Fine, B.M. and Scott, D.W., (2004), “Immunodominant T-cell epitopes in the Factor VIII C2 domain are located within an inhibitory antibody binding site.” Thrombos Haemost 92, 522-28.

Fuentes-Prior, P., Fujikawa, K., and Pratt, K.P., (2002) “New insights into binding interfaces of coagulation factors V and VIII and their homologues – lessons from high-resolution crystal structures”, Current Protein and Peptide Science, 3, 313-339.
 
Spiegel, P.C., Jr., Jacquemin, M, Saint-Remy, J-M.R., Stoddard, B.L., and Pratt, K.P., (2001) Plenary paper: “Structure of a factor VIII C2-domain – Immunoglobulin G4k Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII”, Blood 98(1), 13-19.

Chung, D.W., Pratt, K.P., and Ichinose, A., (2001) “Disorders of Fibrinogen and Factor XIII’, in: The Metabolic and Molecular Bases of Inherited Disease, 8th Edition, McGraw–Hill, Inc..

Pratt, K.P., (2000) “Relating structure to function: the role of the C2 domain in Factor VIII”, Current Opinion in Drug Discovery and Development 3, 1367-1377.

Liu, M.-L., Shen, B.W., Nakaya, S.,Pratt, K.P. , Takeshima , K., Davie, E.W., Fujukawa, K., Stoddard, B.L., and Thompson, A.R. (2000), “Hemophilic factor VIII C1- and C2- domain missense mutations and their modeling to the 1.5-angstrom human C2-domain crystal structure”, Blood 96, 979-987.

Pratt, K.P. , Shen, B.W., Takeshima, K., Davie, E.W., Fujikawa, K., and Stoddard, B.L., (1999), “Structure of the C2 domain of  human factor VIII at 1.5 angstrom resolution”, Nature 402, 439-442.

Côté, H.C.F., Lord, S.T., and Pratt, K.P. , (1998), “g-Chain Dysfibrinogenemias: Molecular Structure-Function Relationships of Naturally-Occurring Mutations in the g Chain of Human Fibrinogen”, Blood 92, 2195-2212.

Côté, H.C.F., Pratt, K.P. , Davie, E.W. & Chung, D.W., (1997) “The primary polymerization site in fibrinogen is separate from the calcium-binding site”, J. Biol. Chem. 272, 23792-23798.

Yee, V.C., Pratt, K.P. , Côté, H.C.F., LeTrong, I., Chung, D.W., Davie, E.W., Stenkamp, R.E. & Teller, D.C., (1997)  “Crystal Structure of a 30 kDa carboxyl terminal fragment from the g chain of human fibrinogen”,Structure 5, 125-138.

Pratt, K.P. , Côté, H.C.F., Chung, D.W., Stenkamp, R.E., Davie, E.W. (1997): The primary fibrin polymerization pocket: Three-dimensional structure of a 30-kDa C-terminal g chain fragment complexed with the peptide Gly-Pro-Arg-Pro.  Proc. Natl. Acad. Sci. USA 94, 7176-7184.

Allen, S.C., Acharya, K.R., Palmer, K.A. , Shapiro, R., Vallee, B.L. & Scheraga, (1994) “A comparison of the predicted and X-ray structures of angiogenin.  Implications for further studies of model building of homologous proteins”, J.  Protein Chem. 13, 649-658.

Zagari, A.,Palmer, K.A. , Gibson, K.D., Némethy, G. & Scheraga, H.A., (1994) “The effect of the L-azetidine-2-carboxylic acid residue on protein conformation. IV. Local substitutions in the collagen triple helix”, Biopolymers34, 51-60.

Némethy, G., Gibson, K.D., Palmer, K.A. , Yoon, C.N., Paterlini, G., Zagari, A., Rumsey, S. & Scheraga, H.A. (1992) “Energy Parameters on Polypeptides. 10. Improved Geometrical Parameters and Nonbonded Interactions for use in the ECEPP/3 Algorithm, with Application to Proline-containing Peptides”, J. Phys. Chem. 96, 6472-6484.

Perrot, G., Cheng, B., Gibson, K.D., Vila, J., Palmer, K.A. , Nayeem, B., Maigret, B. & Scheraga, H.A. (1992) “MSEED: A Program for the Rapid Analytical Determination of Accessible Surface Areas and their Derivatives”, J. Computational Chem. 13, 329-350.

Palmer, K.A. & Scheraga, H.A., (1991) “Standard-Geometry Chains Fitted to X-ray Derived Structures: Validation of the Rigid-Geometry Approximation. I. Chain Closure through a Limited Search of “Loop” Conformations”, J. Computational Chem. 12, 505-526.

Palmer, K.A. & Scheraga, H.A., (1991) “Standard-Geometry Chains Fitted to X-ray Derived Structures: Validation of the Rigid-Geometry Approximation. II. Systematic Searches for Protein Loops: Applications to Bovine Pancreatic Ribonuclease A and Human Lysozyme” (1992) J. Computational Chem. 13, 329-350.

Palmer, K.A. , Scheraga, H.A., Riordan, J.F. & Vallee, B.L., (1986) “A Preliminary Structure of the Protein Angiogenin” Proc. Natl. Acad. Sci. USA 83, 1965-1969.